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Cutting-edge breakthroughs in pain research

Avanos & COOLIEF

As Avanos continues to invest in clinical research in the radiofrequency ablation space, we are proud to announce the publication of a large, randomized, multicentered clinical trial comparing the safety and efficacy of COOLIEF* Cooled Radiofrequency ablation to hyaluronic acid (HA) injection for the management of chronic knee pain caused by osteoarthritis.

The results to the clinical trial include:

  • At the 6-month timepoint, 71.1% of subjects receiving CRFA reported ≥ 50% pain relief compared to 37.8% of subjects receiving HA.
  • Those receiving CRFA had a 48.2% improvement in WOMAC score at 6 months, compared to 22.6% of subjects treated with HA.
  • Additionally, 72.4% of subjects in the CRFA group reported improvements in GPE compared to 40.2% in the HA group.

To read the full manuscript published in the Journal of Bone & Joint Surgery, the official journal of the American Orthopedic Association, click here.

Be sure to also stay tuned to future Avanos communications for 12-month, 18-month and 24-month timepoints from the clinical trial that will be reported in future publications.

Find One Of Our Pain Care Clinics Near You


1301 E 47th St Building 2,
Chicago, IL 60653


2845 N Sheridan Blvd Ste 910,
Chicago, IL 60657


908 N Elm St Ste 301,
Hinsdale, IL 60521

Get in Touch With Pinnacle Pain Care Specialists

Why Pinnacle Pain Management?

As a leader in Pain Management care in the Chicagoland area, Pinnacle Pain Management, we use state-of-the-art pain treatments to diagnose and treat acute and chronic pain. At Pinnacle Pain Management, we believe in treating the whole person and permanent relief to improve your everyday life. Among some of the other top reasons to choose Pinnacle Pain Management includes:

Trusted Leader

Dr. Jain's experience, including serving as Medical Director of Pain Management at Hinsdale Hospital for nearly a decade.

Top Doctor

Dr. Jain, in his time with Pinnacle Pain Management, was named a  Top 5 Pain Specialist in Chicago by Chicago Magazine.

Newest Treatments

Pinnacle offers the newest and trusted pain management services and treatments, such as Intracept and VIA disc.